Key Features and Values
- Ready to use, well characterised Control (number of CGG repeats and % methylation)
- A single control covering multiple size ranges in FMR1 gene (Normal (NOR), Premutation (PM), Full Mutation (FM)
- Amplification of low levels of FM alleles (5%) in presence of NOR and PM alleles (95%)
Product Description
The AmplideX FMR1 Methylation & Sensitivity Control is proprietary mixtures of genomic DNA containing multiple alleles. This well characterised control can be used as process or batch controls covering multiple size ranges and different methylation states in the FMR1 gene.
Publications
- Grasso M, Boon EM, Filipovic-Sadic S, et al: A novel methylation PCR that offers standardized determination of FMR1 methylation and CGG repeat length without southern blot analysis. J Mol Diagn 2014 Jan;16(1):23-31;
