Anti-ds DNA IgG

Key Features and Values

– Same sample type can be used across all assays to simplify inclusion into routine serology work-up
– Ready to use reagents reduces hands-on time for assay preparation
– Long shelf life cost-effective solution by reducing wastage due to expired kits
– Suitable for inclusion on automated plate systems simplifies scale-up of test volume
– Supported by a complete panel of assays for diagnosis of SLE and APS

Product Description

Anti dsDNA IgG kit is an indirect solid phase enzyme immunometric assay (ELISA) designed for the quantitative measurement of IgG class antibodies directed against dsDNA in human serum or plasma.  Anti dsDNA IgG is intended for laboratory use only.

Scientific Description

Anti dsDNA IgG test is used for initial diagnosis of Systemic Lupus Erythematosus (SLE) and for diagnosis of SLE different diseases.  Besides the determination of high titers of antinuclear antibody (ANA), the determination of autoantibodies against dsDNA is one of the ACR criteria (American College of Rheumatology) for the diagnosis of Systemic Lupus Erythematosus (SLE).  The determination of the concentration of antibodies can be used to monitor treatment success and predict possible attacks of the disease (SLE).


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2. Reichlin,M., Van Venrooij, W. J.: Autoantibodies to UNRP particles: relationship to clinical diagnosis and nephritis.Clin.exp.Immunol. 1991; 83:286-90.
3. Tan EM, et al.: The 1982 Revised Criteria for the classification of Systemic Lupus Erythematosus. Arthritis and Rheumatism 25: 1271-1277,1982.
4. McCarty GA. Autoantibodies and their relation to rheumatic diseases. Medical Clinics of North America 70: 237-261, 1986.
5. Hardin JA. The lupus autoantigens and the pathogenesis of systemic lupus erythematosus. Arth Rheum 29: 457-460, 1986.
6. The first international Calibrator for antibodies to double stranded DNA. Annals of the Rheumatic Disease 198; Vo 47: 740 – 746
7. Homburger HA, et al: detection of Antinuclear antibodies, comparative evaluation of enzyme immunoassay and indirect immunofluorescence
methods. Arch Pathol Lab Med 122:993-999 (1998)
8. Smeenk, R. et al. Avidity of Antibodies to dsDNA. Comparation of IFT on Crithidia Lucilaie, FARR assay and PEG assay. The journal of Immunology
1982 Vo 128 n.1. 73 -78

Complementary Products


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Code: DKO095
Clinical Area: ,
Incubation: 45+45+15 min
Sensitivity: >99%
Specificity: >99%
Classification: IVD, CE
Number of Tests: 96
Sample Type: Serum/Plasma
Sample Volume: 10 µL (1:100 predilution)
Assay Range: N/A